Combined xeno/auto-grafting of a benign osteolytic lesion in a dog, using a novel bovine cancellous bone biomaterial
| Autor: | Andrew J. Worth, Mucalo, Keith G. Thompson, Elwyn C. Firth, M C Owen |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Transplantation Heterologous Transplantation Autologous Osseointegration Dogs Biopsy medicine Animals Quantitative computed tomography Bone Transplantation General Veterinary medicine.diagnostic_test business.industry Fibrous dysplasia Jamshidi needle General Medicine Aneurysmal bone cyst medicine.disease Curettage Radiography Radius Treatment Outcome medicine.anatomical_structure Female Radiology business Cancellous bone |
| Zdroj: | New Zealand Veterinary Journal. 55:143-148 |
| ISSN: | 1176-0710 0048-0169 |
| DOI: | 10.1080/00480169.2007.36758 |
| Popis: | A 4-year-old female Labrador Retriever was diagnosed with an osteolytic lesion of the right distal radius.Radiographs indicated a well-circumscribed radiolucent area 18 x 15 x 8 mm, centred on the distal radial physeal scar.Histopathology, performed via Jamshidi needle biopsy and following surgical curettage, was inconclusive but suggested either an aneurysmal bone cyst or fibrous dysplasia.A novel processed cancellous bovine bone xenograft was used in conjunction with autogenous cancellous bone (at a ratio of approximately 4:1) to fill the curetted defect. There were no observed complications associated with the use of this new biomaterial. Osteointegration of the bone graft was followed using conventional radiographs and peripheral quantitative computed tomography (pQCT) for 10 months post-operatively. Radiographically, the osteolytic lesion modelled to resemble metaphyseal trabeculation. The cross-sectional area and the average bone density of the grafted lesion determined using pQCT data increased over time, suggesting healthy osteoconduction and native bone production. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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