Convenient one-pot synthesis of 2-oxazolines from carboxylic acids
| Autor: | Yumiko Takechi, Hiroyuki Tanaka, Kazuhito Hioki, Noriyo Kimura, Munetaka Kunishima |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
chemistry.chemical_classification
Magnetic Resonance Spectroscopy Spectrophotometry Infrared Potassium Compounds Carboxylic acid Methanol One-pot synthesis Carboxylic Acids General Chemistry General Medicine Oxazoline Nuclear magnetic resonance spectroscopy Chloride chemistry.chemical_compound chemistry Drug Discovery medicine Hydroxides Organic chemistry Indicators and Reagents Oxazoles medicine.drug |
| Zdroj: | Chemicalpharmaceutical bulletin. 56(12) |
| ISSN: | 0009-2363 |
| Popis: | Simple one-pot methods for preparation of 2-oxazolines have been developed using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM). Treatment of a mixture of carboxylic acids and 2-haloethylammonium salts with DMT-MM in methanol followed by refluxing in the presence of KOH gives oxazolines. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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