Evaluation of right ventricular dyssynchrony in patients with acute inferior myocardial infarction and its relation with mortality
| Autor: | Alper Kepez, Emre Gürel, Murat Sunbul, Beste Özben Sadıç, Mustafa Kürşat Tigen, Nurten Sayar, Ahmet Altuğ Çinçin, Batur Gonenc Kanar |
|---|---|
| Přispěvatelé: | Kanar, Batur Gonenc, Tigen, Mustafa Kursat, Sunbul, Murat, Cincin, Ahmet Altug, Gurel, Emre, Sayar, Nurten, Kepez, Alper, Sadic, Beste Ozben |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
SPECKLE-TRACKING ECHOCARDIOGRAPHY STRAIN Heart Ventricles Ventricular Dysfunction Right medicine.medical_treatment Acute Inferior Myocardial Infarction Speckle tracking echocardiography inferior myocardial infarction Inferior Wall Myocardial Infarction 030204 cardiovascular system & hematology Free wall 03 medical and health sciences 0302 clinical medicine cardiovascular mortality Internal medicine medicine Humans Radiology Nuclear Medicine and imaging In patient ventricular dyssynchrony 030212 general & internal medicine Ventricular dyssynchrony Cardiovascular mortality business.industry Percutaneous coronary intervention medicine.disease right ventricular infarction Coronary Vessels PREVALENCE medicine.anatomical_structure Echocardiography Ventricle Ventricular Function Right Cardiology Cardiology and Cardiovascular Medicine business |
| Popis: | Purpose The aim of this study was to evaluate right ventricle (RV) dyssynchrony and its relation with mortality using speckle-tracking echocardiography (STE) in patients with acute inferior myocardial infarction (IMI). Methods One hundred and fifty-eight consecutive patients with acute IMI treated with primary percutaneous coronary intervention, and 44 healthy subjects were included. RV myocardial involvement (RVMI) was defined as an elevation >1 mm in V1 or V4R and/or the presence of a culprit lesion at the proximal portion of the first RV marginal branch after reviewing coronary angiography. Patients were followed for 3 years to determine the cardiovascular mortality. Results Overall, 70 patients with IMI had RVMI. IMI patients had significantly higher RV peak systolic longitudinal strain dyssynchrony (PLSSD) index, lower peak longitudinal systolic strain (PLSS), longer time to PLSS, and time to PLSS differences compared to healthy controls while the patients with RVMI had significantly worse values compared to patients without RVMI and healthy controls. Twenty-seven patients (17.1%) died within 2 years. RVMI was more prevalent in mortality group, and they had significantly higher RV PSSD index, whereas they had lower RV free wall PLSS and longer time to PLSS differences. Receiver operating characteristics (ROC) analysis revealed that a RV PLSSD index > 65 ms predicted mortality with a sensitivity of 88.9% and specificity of 71.8% in IMI patients. Conclusions Intra- and inter-ventricular dyssynhcrony may develop in patients with acute IMI, especially in those with RV involvement, which might have a negative effect on the prognosis of these patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|