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Introduction: Spinal anaesthesia has been the preferred choice for caesarean section now a days. Suitable analgesia after caesarean sectionhelps mothers to be more comfortable and increases their ability to take better care of their infants. Postoperative pain has numerous side effects, including atelectasis, thrombosis, myocardial ischemia, cardiac arrhythmias, electrolyte imbalance, ileus, and urinary retention. This study is designed to estimate the duration of postoperative analgesia using low dose intravenous ketamine as used in the parent study. Objective To compare the mean duration of postoperative analgesia between low dose intravenous ketamine with intrathecal Bupivacaine and intrathecal Bupivacaine alone in patients undergoing elective caesarean section under spinal anaesthesia. ● Setting :This study was conducted at Department of Anaesthesiology, Surgical Intensive Care Unit and Pain Management Clinic, Dow University of Health Sciences, Dr. Ruth K. M. Pfau Civil Hospital Karachi, Pakistan. ● Duration: 6 months ( from 24th February 2017 to 23rd August 2017). ● Design: Randomized Controlled Trial, Subject and Methods Patients were presented in elective Obstetric operation theatre of Dr. Ruth K. M. Pfau Civil Hospital Karachi. A total of 60 women undergoing elective caesarean section were randomly allocated into two groups. Thirty were treated with bupivacaine-ketamine (group BK) and 30 were treated with bupivacaine alone (group B). Duration of postoperative analgesia was assessed every 30 minutes using VAS numeric pain scale by a single observer were blinding to group allocation. The end point of the study was when VAS score ≥4 or when patients requested for analgesia postoperatively. Results The average ageand weight of the patients was 27.50±4.80 years and 59.37+- 6.83 kg respectively in group BK, and 25.93±5.33 years and 63.47+-5.74 kg in group B as tabulated in table 1. Mean duration of analgesia was significantly high in group BK as compare to group B [3.85±0.98h vs. 1.40±0.62 h; p=0.0005]. Conclusion Intravenous low-dose ketamine during spinal anaesthesia for elective caesarean section provides more effective and long lasting pain relief than control group. |
