Acute Aortic Dissection Type A : Age-related Management and Outcomes Reported in the German Registry for Acute Aortic Dissection Type A (GERAADA) of Over 2000 Patients
| Autor: | Rylski, Bartosz, Hoffmann, Isabell, Beyersdorf, Friedhelm, Suedkamp, Michael, Siepe, Matthias, Nitsch, Brigitte, Blettner, Maria, Borger, Michael Andrew, Weigang, Ernst, Mohr, Friedrich Wilhelm, Moritz, Anton, Karck, Matthias, Beyer, Michael, Schlensak, Christian, Hagl, Christian, Reichenspurner, Hermann, Vahl, Christian-Friedrich, Harringer, Wolfgang, Dapunt, Otto, Carrel, Thierry, Diegeler, Anno, Jakob, Heinz G., Laufer, Günther, Liebold, Andreas, Warnecke, Henning, Matschke, Klaus, Sievers, Hans-Hinrich, Welz, Armin, Walther, Thomas, Fischlein, Theodor, Leyh, Rainer, Däbritz, Sabine, Schäfers, Hans-Joachim, Peivandi, Ali Asghar, Martens, Sven, Massoudy-Touiserkan, Parwis, Rieß, Friedrich-Christian, Gummert, Jan, Cremer, Jochen, Autschbach, Rüdiger, Ennker, Jürgen, Posival, Herbert, Markewitz, Andreas, Schütz, Albert, Wimmer-Greinecker, Gerhard, Steinhoff, Gustav, Dahm, Manfred, Franke, Ulrich, Dörge, Hilmar, Vetter, Herbert, Doenst, Torsten, Kuntze, Thomas, Wahlers, Thorsten, Hausmann, Harald, Haverich, Axel, Doll, Nicolas, Silber, Rolf-Edgar, Hammel, Dieter |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Medizin law.invention Young Adult Aortic aneurysm Sex Factors Aneurysm Randomized controlled trial law Germany medicine Humans Prospective Studies Registries Young adult Prospective cohort study Aged Aortic dissection Aortic Aneurysm Thoracic business.industry fungi Age Factors Middle Aged Prognosis medicine.disease Surgery Survival Rate Aortic Dissection Cardiothoracic surgery Austria Female Morbidity business Vascular Surgical Procedures Switzerland Aortic Aneurysm Abdominal Follow-Up Studies Abdominal surgery |
| Popis: | To determine the association between age and clinical presentation, management and surgical outcomes in a large contemporary, prospective cohort of patients with acute aortic dissection type A (AADA).AADA is one of the most life-threatening cardiovascular diseases, and delayed surgery or overly conservative management can result in sudden death.The perioperative and intraoperative conditions of 2137 patients prospectively reported to the multicenter German Registry for Acute Aortic Dissection Type A were analyzed.Of all patients with AADA, 640 (30%) were 70 years or older and 160 patients (7%) were younger than 40 years. The probability of aortic dissection extension to the supra-aortic vessels and abdominal aorta decreased with age (P0.0001 and P = 0.0017, respectively). In 1447 patients (69%), the aortic root was preserved and supracoronary replacement of the ascending aorta was done. The probability of this procedure increased with age (P0.0001). The incidence of new postoperative neurological disorders was not influenced by age. The lowest probability of 30-day mortality was noted in the youngest patients (11%-14% for patients aged between 20 and 40 years) and rose progressively with age, peaking at 25% in octogenarians.This study reflects current results after surgical treatment of AADA in relation to patient age. Current survival rates are acceptable, even in very elderly patients. The contemporary surgical mortality rate among young patients is lower than that previously reported in the literature. The postoperative stroke incidence does not increase with age. |
| Databáze: | OpenAIRE |
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