Chlamydia trachomatis among Patients Infected with and Treated for Neisseria gonorrhoeae in Sexually Transmitted Disease Clinics in the United States
| Autor: | Sheryl B. Lyss, Jonathan M. Zenilman, Daniel R. Newman, C. Kevin Malotte, John S. Moran, Wilbert J. Newhall, Michael Iatesta, Thomas A. Peterman, Charlotte A. Gaydos, John M. Douglas, Gail Bolan, Mary L. Kamb, Josephine Ehret |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Sexually transmitted disease medicine.medical_specialty Gonorrhea Chlamydia trachomatis urologic and male genital diseases medicine.disease_cause Internal medicine Epidemiology Internal Medicine medicine Humans Chlamydiaceae Chlamydia biology business.industry General Medicine Chlamydia Infections biology.organism_classification medicine.disease Virology Neisseria gonorrhoeae United States female genital diseases and pregnancy complications Cross-Sectional Studies Chlamydiales Practice Guidelines as Topic Female business |
| Zdroj: | Annals of Internal Medicine. 139:178 |
| ISSN: | 0003-4819 |
| DOI: | 10.7326/0003-4819-139-3-200308050-00007 |
| Popis: | For two decades, treatment guidelines for sexually transmitted diseases (STDs) have recommended empirical co-treatment for chlamydia when patients are treated for gonorrhea. Because the epidemiology of and diagnostic testing for STDs have changed over time, co-treatment may no longer be needed as a clinical or public health strategy.To assess the prevalence of chlamydia among patients at STD clinics who are infected with and treated for Neisseria gonorrhoeae and to determine whether co-treatment recommendations are still justified.Cross-sectional analysis of data from a multisite study.Five public STD clinics (Baltimore, Maryland; Denver, Colorado; Long Beach, California; Newark, New Jersey; and San Francisco, California), July 1993 through October 1995.3885 heterosexual patients (2184 men and 1701 women) who agreed to participate in a trial of counseling interventions and had conclusive results from diagnostic tests for gonorrhea and chlamydia performed routinely as part of the trial.Infection with Chlamydia trachomatis as determined by polymerase chain reaction.Chlamydia trachomatis was detected in 20% (95% CI, 16% to 24%) of 411 men and 42% (CI, 35% to 50%) of 151 women with laboratory-confirmed N. gonorrhoeae. Chlamydia trachomatis was detected in 19% (CI, 15% to 22%) of 410 men and 35% (CI, 28% to 43%) of 154 women with treatment indications for gonorrhea who would not otherwise have been treated for chlamydia: chlamydia prevalence among these patients was significantly higher than among patients without treatment indications for either gonorrhea or chlamydia: 7% in men and 9% in women (relative risk, 2.58 [CI, 1.92 to 3.47] and 4.12 [CI, 3.05 to 5.57], respectively).The frequent presence of chlamydia among patients at STD clinics who received treatment for gonorrhea, including sex partners of gonorrhea-infected patients, supports continuing current recommendations for co-treatment. |
| Databáze: | OpenAIRE |
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