Can the conventional sextant prostate biopsy accurately predict unilateral prostate cancer in low-risk, localized, prostate cancer?
| Autor: | Leon Sun, John F. Madden, Thomas J. Polascik, Vladimir Mouraviev, Janice M. Mayes, Matvey Tsivian |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Prostate biopsy Urology medicine.medical_treatment law.invention Prostate cancer Predictive Value of Tests law Prostate Biopsy Humans Medicine Sextant Aged Prostatectomy medicine.diagnostic_test business.industry Biopsy Needle Prostatic Neoplasms Reproducibility of Results Middle Aged Prognosis medicine.disease medicine.anatomical_structure Oncology Prostate surgery Prostate neoplasm business |
| Zdroj: | Urologic Oncology: Seminars and Original Investigations. 29:166-170 |
| ISSN: | 1078-1439 |
| DOI: | 10.1016/j.urolonc.2009.03.011 |
| Popis: | We evaluate the reliability of routine sextant prostate biopsy to detect unilateral lesions. A total of 365 men with complete records including all clinical and pathologic variables who underwent a preoperative sextant biopsy and subsequent radical prostatectomy (RP) for clinically localized prostate cancer at our medical center between January 1996 and December 2006 were identified. When the sextant biopsy detects unilateral disease, according to RP results, the NPV is high (91%) with a low false negative rate (9%). However, the sextant biopsy has a PPV of 28% with a high false positive rate (72%). Therefore, a routine sextant prostate biopsy cannot provide reliable, accurate information about the unilaterality of tumor lesion(s). |
| Databáze: | OpenAIRE |
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