Ruthenium polypyridyl complexes; their interactions with DNA and their role as sensitizers for its fotocleavage

Autor:	Alessandro Tossi, David J. McConnell, A. Masschelein, John M. Kelly, Colm OhUigin, Andrée Kirsch-De Mesmaeker, Jacques Nasielski
Přispěvatelé:	J. M., Kelly, D. J., Mcconnell, C., Ouuigin, Tossi, Alessandro, A., KIRSH DEMESMAEKER, A. MASSCHELEIN J., Nasielski
Jazyk:	angličtina
Rok vydání:	1987
Předmět:	oligonucleotide photochemistry photophysic Photodissociation chemistry.chemical_element Cleavage (embryo) Photochemistry Medicinal chemistry Ruthenium chemistry.chemical_compound chemistry Excited state Molecular Medicine time resolved fluorescence ruthenium polypyridyl photophysics DNA
Zdroj:	Scopus-Elsevier
Popis:	The excited state of the 1,4,5,8-tetra-azaphenanthrene complex, [Ru(TAP)3]2+, which unlike [Ru(phen)3]2+(phen = 1,10-phenanthroline) or [Ru(bipy)3]2+(bipy = 2,2′-bipyridyl) is strongly quenched upon binding to poly[d(G–C)], is found to be much more effective than either [Ru(phen)3]2+ or [Ru(bipy)3]2+ in causing cleavage of the DNA backbone.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e90921f5ee3c78206047eda9be0494 http://hdl.handle.net/11368/1710290 Zobrazit plný text záznamu