Granulocyte Transfusions in Acute Leukaemia Regeneration of Granulopoiesis as Determining Factor of Survival
| Autor: | Markus Wiesneth, M. Dietrich, Hermann Heimpel, Bernhard Kubanek, H. Rasche, Renate Arnold, S Bhaduri, H Pflieger |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Granulocyte Granulopoiesis Sepsis hemic and lymphatic diseases Internal medicine medicine Humans Blood Transfusion Child Aged Body surface area Leukemia business.industry Regeneration (biology) Hematology Middle Aged Hematopoiesis Leukemia Myeloid Acute medicine.anatomical_structure Leukemia Myeloid Child Preschool Acute Disease Immunology Transfusion therapy business Granulocytes |
| Zdroj: | Scandinavian Journal of Haematology. 26:215-220 |
| ISSN: | 0036-553X |
| DOI: | 10.1111/j.1600-0609.1981.tb01649.x |
| Popis: | 40 patients with acute leukaemia and severe granulocytopenia were treated with granulocyte transfusions for bacteriologically documented or clinically suspected septicaemia. The patients received an average of 5 transfusions each with 2.1 times 1010 granulocytes per m2 body surface area per day. 26 patients showed clinical benefit from transfusion therapy as documented by the course of blood cultures, local lesions and fever. Only patients with regeneration of granulopoiesis had definite benefit from granulocyte transfusions. All other patients died ultimately from septicaemia. |
| Databáze: | OpenAIRE |
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