Progressive massive fibrosis in workers outside the coal industry: A case series from New Mexico

Autor: Sapna Bhatia, Landon Casaus, Akshay Sood
Rok vydání: 2019
Předmět:
Zdroj: Southwest Journal of Pulmonary and Critical Care, Vol 18, Iss 1, Pp 10-19 (2019)
ISSN: 2160-6773
DOI: 10.13175/swjpcc110-18
Popis: Four clinical patterns of diffuse lung disease may be seen with silicosis: acute silicosis or silicoproteinosis (the latter resembling pulmonary alveolar proteinosis), simple nodular sclerosis, accelerated silicosis, and progressive massive fibrosis (PMF). The intensity and duration of exposure as well as host susceptibility dictates the presentation and progression of PMF. Although most cases of PMF in the literature are reported among coal miners in whom this disease has shown a recent increase in prevalence, this disease can also be seen in exposed workers outside the coal industry. In this article, we will review the clinical, physiological, and pathological manifestations of the disease, illustrated by three case examples of PMF among non-coal miners from New Mexico. Diagnosis and management of patients with PMF can be difficult, and carries medicolegal implications for the patient. Physicians and policymakers need to be aware of PMF in workers exposed to silica within and outside the coal industry.
Databáze: OpenAIRE