'Shunt index' can be used to predict clinically significant patent ductus arteriosus in premature neonates in early post-natal life
| Autor: | Aylin Tarcan, Hande Gulcan, Deniz Anuk Ince, Mahmut Gökdemir, Ayşe Ecevit, Birgin Torer, Ece Yapakci |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Vena cava Ibuprofen Vena Cava Inferior Ductus arteriosus Internal medicine medicine Humans Cyclooxygenase Inhibitors cardiovascular diseases Ductus Arteriosus Patent Blood gas analysis business.industry Infant Newborn Arteries General Medicine Venous blood Shunt (medical) Oxygen medicine.anatomical_structure Echocardiography Anesthesia embryonic structures Pediatrics Perinatology and Child Health cardiovascular system Cardiology Female Blood Gas Analysis Cardiology and Cardiovascular Medicine business Umbilical catheter Infant Premature medicine.drug Oxygen extraction |
| Zdroj: | Cardiology in the Young. 24:605-609 |
| ISSN: | 1467-1107 1047-9511 |
| DOI: | 10.1017/s1047951113000772 |
| Popis: | Background:This study aimed to examine the differences between arterial and inferior caval vein oxygen saturation, fractional oxygen extraction, and the shunt index, which were calculated in the diagnosis of patent ductus arteriosus.Methods:Twenty-seven preterm infants were included in this study and were divided into two groups according to patent ductus arteriosus. Among them, 11 (41%) infants had haemodynamically significant patent ductus arteriosus and 16 (59%) did not have significant patent ductus arteriosus. Synchronous arterial and venous blood gases were measured during the first post-natal hours after the insertion of umbilical catheters. The differences between arterial and inferior caval vein oxygen saturation, inferior body fractional oxygen extraction, and the shunt index were calculated. Echocardiography was performed before the 72nd hour of life in a selected group of patients who had haemodynamically significant patent ductus arteriosus. Ibuprofen treatment was administered to patients with patent ductus arteriosus. Echocardiography was performed on the 72nd hour of life in preterm infants without any clinical suspicion of patent ductus arteriosus.Results:The early measured differences between arterial and inferior caval vein oxygen saturation and inferior body fractional oxygen extraction were found to be lower and the shunt index was found to be higher in the haemodynamically significant patent ductus arteriosus group than in the group without haemodynamically significant patent ductus arteriosus.Conclusion:We found that the shunt index, calculated in the first hours of life as ≥63%, predicted haemodynamically significant patent ductus arteriosus with a sensitivity of 78% and specificity of 82% in preterm newborns. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|