TRANSDIFFERENTIATION OF MULTIPOTENT MESENCHYMAL STROMAL CELLS BY GENETIC ENGINEERING METHODS TO OBTAIN HEPATOCYTES

Autor:	Makeyev O., Korotkov A., Satonkina O., Schumann E., Desyatova M.
Rok vydání:	2022
Předmět:	multipotent mesenchymal stromal cells transdifferentiation hepatocytes
DOI:	10.5281/zenodo.7408569
Popis:	Therapy of liver failure is a insufficiently resolved problem. One of the options for its solution it is a liver transplantation. However, this method has a number of drawbacks, which include a limited number of donors and transplant rejection. The use of autologous hepatocytes would allow significant progress to solve the problem under discussion. The work considers a method that allowed obtaining autologous hepatocytes by transdifferentiation of multipotent mesenchymal stromal cells using genetic engineering methods.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b846fe8bca8fc8ff6bf8d7a02dd25f Zobrazit plný text záznamu