Intense sport practices and cardiac biomarkers
| Autor: | Patrice Dufour, C. Le Goff, Etienne Cavalier, Jean-François Kaux, J. Farre Segura |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
030213 general clinical medicine
medicine.medical_specialty Cardiac fibrosis Galectin 3 Galectins Clinical Biochemistry 030204 cardiovascular system & hematology Running 03 medical and health sciences 0302 clinical medicine Fibrosis Internal medicine medicine Humans Myocardial infarction Natriuretic Peptides biology Athletes Mechanism (biology) business.industry Myocardium Glycopeptides Blood Proteins General Medicine medicine.disease biology.organism_classification Interleukin-1 Receptor-Like 1 Protein Troponin MicroRNAs Heart failure biology.protein Cardiology Biomarker (medicine) business Biomarkers |
| Zdroj: | Clinical Biochemistry. 79:1-8 |
| ISSN: | 0009-9120 |
| DOI: | 10.1016/j.clinbiochem.2020.02.008 |
| Popis: | Biomarkers are well established for the diagnosis of myocardial infarction, heart failure and cardiac fibrosis. Different papers on cardiac biomarker evolution during exercise have been published in the literature and generally show mild to moderate elevations. However, the mechanism responsible for these elevations, reflecting physiological or even pathophysiological changes, still has to be clearly elucidated. There are also indications of higher cardiac risk in poorly trained athletes than in well-trained athletes. Whether regular repetition of intensive exercise might lead, in the longer term, to fibrosis and heart failure remains to be determined. In this review, we summarized the main research about the effects of intense exercise (in particular, running) on cardiac biomarkers (including troponins, natriuretic peptides, etc.). We found that cardiac fibrosis biomarkers seemed to be the most informative regarding the biological impact of intense physical activity. |
| Databáze: | OpenAIRE |
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