Studies on Cotton Dust in Relation to Byssinosis. Part III: Comparison of Cotton Dust and House Dust by Chemical and Skin Tests

Autor: H. R. Cayton, D. S. Jackson, H. B. Maitland, G. Furness
Rok vydání: 1952
Předmět:
Zdroj: Occupational and Environmental Medicine. 9:303-308
ISSN: 1351-0711
DOI: 10.1136/oem.9.4.303
Popis: In an earlier paper Cayton, Furness, and Maitland (1952) showed that extracts of cotton dust produced two types of skin reaction, an early reaction of wheal and flare and a late reaction of induration and erythema. These two reactions appeared to be caused by different substances. The late reaction was possibly a direct effect of some toxic component. The early reaction was of the type associated with allergy of the asthma-urticaria type, but it did not denote specific hypersensitivity peculiar to byssinosis because other groups of the adult urban population reacted equally with byssinotics although they had never been exposed to cotton dust and did not suffer from any allergic symptoms. The early reaction may, however, have indicated hypersensi tivity to an allergen that was widely distributed. In continuing this work preliminary chemical testing of cotton dust extracts suggested the possi bility that they might contain similar components to those reported for house dust extracts by Rimington, Stillwell, and Maunsell (1947). House dust extracts also elicited the early type of skin reaction (Maun sell, Whetnall, and Rimington 1947). The further comparison of a cotton dust extract with house dust extracts is the subject of this paper.
Databáze: OpenAIRE