Nutrition, genetic variation and male fertility
| Autor: | Konrad Samsel, Matineh Rastegar Panah, Bibiana García-Bailo, Judith Dockray, Patricia Grace-Farfaglia, Keith Jarvi, Ahmed El-Sohemy, Shelley M Vanderhout |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Infertility 030219 obstetrics & reproductive medicine business.industry Urology media_common.quotation_subject Physiology Fertility Review Article on Genetic Causes and Management of Male Infertility Biology Micronutrient medicine.disease Nutrigenetics 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Nutrient Nutrigenomics Reproductive Medicine Genetic variation medicine business Reproductive health media_common |
| Zdroj: | Transl Androl Urol |
| ISSN: | 2223-4691 2223-4683 |
| DOI: | 10.21037/tau-20-592 |
| Popis: | Infertility affects nearly 50 million couples worldwide, with 40−50% of cases having a male factor component. It is well established that nutritional status impacts reproductive development, health and function, although the exact mechanisms have not been fully elucidated. Genetic variation that affects nutrient metabolism may impact fertility through nutrigenetic mechanisms. This review summarizes current knowledge on the role of several dietary components (vitamins A, B(12), C, D, E, folate, betaine, choline, calcium, iron, caffeine, fiber, sugar, dietary fat, and gluten) in male reproductive health. Evidence of gene-nutrient interactions and their potential effect on fertility is also examined. Understanding the relationship between genetic variation, nutrition and male fertility is key to developing personalized, DNA-based dietary recommendations to enhance the fertility of men who have difficulty conceiving. |
| Databáze: | OpenAIRE |
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