Effect of epigallocatechin-3- gallate solutions on bond durability at the adhesive interface in caries-affected dentin
| Autor: | Viviane Hass, Melissa Proença Nogueira Fialho, Fabiana Mantovani Gomes França, Flávia Lucisano Botelho do Amaral, Rodrigo Proença Nogueira, Cecilia Pedroso Turssi, Roberta Tarkany Basting |
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| Rok vydání: | 2018 |
| Předmět: |
Molar
Time Factors Biomedical Engineering Dentistry 02 engineering and technology Dental Caries Catechin Biomaterials 03 medical and health sciences 0302 clinical medicine stomatognathic system Caries affected dentin Dentin medicine Humans Bond strength business.industry Chemistry Chlorhexidine Dental Bonding Adhesiveness 030206 dentistry Gallate 021001 nanoscience & nanotechnology Durability Solutions medicine.anatomical_structure Mechanics of Materials Adhesive 0210 nano-technology business medicine.drug |
| Zdroj: | Journal of the mechanical behavior of biomedical materials. 91 |
| ISSN: | 1878-0180 |
| Popis: | Hydrolytic and enzymatic degradation by matrix metalloproteinases (MMPs) reduces the durability of composite resin restorations on caries-affected dentin (CAD). The use of MMP inhibitors such as epigallocatechin-3-gallate (EGCG) could increase the longevity of the bond to dentin. This study aimed to evaluate the use of EGCG at different aqueous concentrations on the resin-dentin microtensile bond strength (μTBS), fracture pattern and nanoleakage (NL) in immediate (IM) time interval and after 12-months of water storage (1Y) when using a two-step etch-and-rinse adhesive system on CAD. Dentin surfaces of 40 human molars were submitted to a microbiological caries induction protocol and randomized into 5 groups (n = 8) (0.02% EGCG; 0.2% EGCG; 0.5% EGCG; 2% Chlorhexidine [CHX] and no treatment as Control Group - [NT]). After acid etching, the solutions were applied for 60 s followed by application of dental adhesive (Adper Single Bond 2, 3 M ESPE) to CAD surfaces. Subsequently, a resin composite (4 mm) block was built on the dentin. After 24 h, the teeth were sectioned into beam-shaped specimens (cross-sectional area of 1 mm2 and 8-mm high). Half of the specimens were tested in IM and the other half after 1Y. Two samples per tooth were submitted to SEM for NL evaluation. Data were statistically analyzed by two-way ANOVA and Tukey tests (α = 0.05). The results showed that use of EGCG and CHX did not affect μTBS in IM (p > 0.05). After 1Y, there was a reduction in μTBS for all experimental groups (p |
| Databáze: | OpenAIRE |
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