Outcomes of liver transplant recipients with high MELD scores: an experience from a Canadian centre
| Autor: | Michael S, Bleszynski, Subin, Punnen, Sameer, Desai, Trana, Hussaini, Vladimir, Marquez, Eric M, Yoshida, Saumya, Jayakumar, Stephanie, Chartier-Plante, Maja, Segedi, Charles H, Scudamore, Stephen, Chung, Andrzej K, Buczkowski, Peter T W, Kim |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Canadian Journal of Surgery. 65:E425-E439 |
| ISSN: | 1488-2310 0008-428X |
| DOI: | 10.1503/cjs.025520 |
| Popis: | The frequency with which patients with high Model for End-Stage Liver Disease (MELD) scores undergo liver transplantation has been increasing. Canadian literature regarding the outcomes of liver transplantation in recipients with high MELD scores is limited. The primary objective of this study was to assess patient and graft survival among recipients with high (35) and low (≤ 35) MELD scores. Secondary objectives were to potentially identify independent predictors of graft failure and patient mortality.We conducted a retrospective chart review of patients undergoing liver transplantation at a single Canadian centre from 2012 to 2017.A total of 332 patients were included in the study: 280 patients had a MELD score of 35 or lower, and 52 had a MELD score above 35. Patients with high MELD scores had higher rates of pretransplant acute kidney injury and dialysis (No difference in patient mortality was found between MELD groups. Graft survival was significantly lower in recipients with MELD scores above 35. D-MELD may potentially be used as an adjunct in determining risk of graft failure in recipients with high MELD scores. |
| Databáze: | OpenAIRE |
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