Persistence of oral pre-exposure prophylaxis (PrEP) among adolescent girls and young women initiating PrEP for HIV prevention in Kenya
| Autor: | Stephanie Zobrist, Sahar Z Zangeneh, Daniel Oluoch Madiang, Gordon Okomo, Kira Mori, Jean de Dieu Tapsoba, Ann Duerr, Eline Appelmans, Janice Tao, Paul K. Drain, Stanley Bii, Martha Brady, Lily Peng, Jane Cover, Christopher O. Obong'o, Ying Qing Chen, James Mukabi, Rael Obanda, Siavash Pasalar |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Health (social science) Social Psychology Adolescent Anti-HIV Agents Sexual Behavior Human immunodeficiency virus (HIV) HIV Infections medicine.disease_cause Article Persistence (computer science) 03 medical and health sciences Pre-exposure prophylaxis 0302 clinical medicine medicine Humans 030212 general & internal medicine 030505 public health business.industry Mentors Public Health Environmental and Occupational Health Kenya humanities Family medicine Female Pre-Exposure Prophylaxis 0305 other medical science business |
| Zdroj: | AIDS Care |
| ISSN: | 1360-0451 |
| Popis: | The Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) Initiative aims to reduce HIV infections among adolescent girls and young women (AGYW) in Africa. Oral pre-exposure prophylaxis (PrEP) is offered through DREAMS in Kenya to eligible AGYW in high burden counties including Kisumu and Homa Bay. This study examines PrEP persistence among AGYW in high burden community-based PrEP delivery settings. We evaluated PrEP persistence among AGYW in the DREAMS PrEP program in Kisumu and Homa Bay using survival analysis and programmatic PrEP refill data collected between March through December 2017. Among 1,259 AGYW who initiated PrEP during the study period, the median persistence time in the program was 56 days (95% CI: 49-58 days) and the proportion who persisted 3 months later was 37% (95% CI: 34-40%). Persistence varied by county (p |
| Databáze: | OpenAIRE |
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