Timing of commencement of maintenance dialysis and mortality in young and older adults in Singapore

Autor: Ai Zhen Jin, Liang Feng, Khuan Yew Chow, John Carson Allen, Tazeen H. Jafar
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: BMC Nephrology, Vol 18, Iss 1, Pp 1-10 (2017)
BMC Nephrology
ISSN: 1471-2369
DOI: 10.1186/s12882-017-0590-x
Popis: Background The benefit of early dialysis initiation remains controversial with a paucity of data in Asians. Therefore, we undertook this study to investigate the association between timing of initiation of dialysis and mortality in Singapore. Methods The study used data from the Singapore Renal Registry database on 3286 patients with incident end-stage renal disease (ESRD) who commenced maintenance dialysis between January 2008 and December 2011. The data was further linked with the National Death Registry to acquire survival information until December 2013. We classified serum creatinine-based, estimated glomerular filtration rate (eGFR) by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation at the start of dialysis into 3 categories: Early (≥10 ml/min/1.73m2), intermediate (5 to
Databáze: OpenAIRE