Water-pipe smoking and serum testosterone levels in adult males in Qatar
| Autor: | Ala-Eddin Al Moustafa, Mona Saad, Anas A Ashour, Reem S Mubarak, Wafaa A Mohamed, Yaman M AlAhmad, Maha M Hussein, Fajer A. Al-Ishaq, Mahmoud Y Haik |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Health (social science) medicine.medical_treatment education bioavailable testosterone Medicine (miscellaneous) 030209 endocrinology & metabolism lcsh:RC254-282 03 medical and health sciences 0302 clinical medicine Sex hormone-binding globulin Water Pipe Smoking Internal medicine Epidemiology Medicine 030212 general & internal medicine water-pipe smoking Serum testosterone lcsh:RC705-779 free testosterone Free testosterone biology business.industry Public Health Environmental and Occupational Health Testosterone (patch) lcsh:Diseases of the respiratory system lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens sex hormone binding globulin Endocrinology Bioavailable Testosterone biology.protein Smoking cessation business Research Paper |
| Zdroj: | Tobacco Induced Diseases, Vol 17, Iss March (2019) Tobacco Induced Diseases |
| Popis: | Water-pipe (WP) smoking is the most common method of tobacco consumption in the Middle-East and is rapidly spreading on a global scale. Although, water-pipe smoking is linked to various diseases, such as emphysema and various types of cancers, its effect on testosterone levels has yet to be investigated. This study explores the effect of water-pipe smoking on serum testosterone levels in males in Qatar. In this cross-sectional sample within a cohort study, we retrieved data for a total of 1000 male volunteers from the Qatar BioBank (QBB) project. A self-reported questionnaire was used to determine the water-pipe smoking status of participants. Moreover, participants were stratified based on the frequency of smoking. Total testosterone and sex hormone binding globulin (SHBG) were measured clinically, whereas free testosterone and bioavailable testosterone were calculated using Vermeulen's equation. Hormone values of 541 males (277 water-pipe smokers and 264 non-smokers) were compared using multiple regression analysis based on water-pipe smoking status after adjusting for confounding factors. No statistically significant difference was observed between WP smokers and non-water-pipe smokers in the likelihood of having lower or higher total testosterone, after adjustment for confounding factors. Similar results were found in free testosterone, bioavailable testosterone, and sex hormone binding globulin (all p>0.05). When compared with the reference group, both light and heavy water-pipe smokers had a similar likelihood of circulating low total testosterone levels (OR=0.83, 95% CI: 0.46-1.49; and OR=0.80, 95% CI: 0.43-1.49; respectively). Our results reveal, for the first time, that there is no significant change in total testosterone, free testosterone, bioavailable testosterone and sex hormone binding globulin in waterpipe smokers compared to non-water-pipe smokers. Therefore, we believe that further studies are needed to confirm the effect of water-pipe smoking on testosterone in different populations. This work was supported by the College of Medicine of Qatar University and grant QUST-2-CMED-2018-1 from Qatar University. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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