Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering
| Autor: | J.L. Gómez Ribelles, R. Brı́gido Diego, M. Pérez Olmedilla, M. Monleón Pradas, A. Serrano Aroca, Gloria Gallego Ferrer, M. Salmerón Sánchez |
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| Rok vydání: | 2004 |
| Předmět: |
Materials science
Scanning electron microscope Surface Properties Biomedical Engineering Biophysics Cell Culture Techniques Bioengineering Biocompatible Materials (Hydroxyethyl)methacrylate Absorption Biomaterials chemistry.chemical_compound Polymethacrylic Acids Polymer chemistry Materials Testing Copolymer Particle Size Porosity Polyhydroxyethyl Methacrylate Tissue Engineering Comonomer technology industry and agriculture Water Microspheres Chemical engineering chemistry Ethyl acrylate Methacrylates Particle size Absorption (chemistry) Crystallization Hydrophobic and Hydrophilic Interactions |
| Zdroj: | Journal of materials science. Materials in medicine. 16(8) |
| ISSN: | 0957-4530 |
| Popis: | Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition. |
| Databáze: | OpenAIRE |
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