Androgens and bladder outlet obstruction: a correlation with pressure-flow variables in a preliminary study
| Autor: | George Koritsiadis, Ioannis Fokitis, S. Koritsiadis, Konstantinos Stravodimos, Dionisios Mitropoulos, Grigorios Doumanis, Constantinos Constantinides |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Urology Prostatic Hyperplasia urologic and male genital diseases Bladder outlet obstruction Lower urinary tract symptoms Prostate medicine Pressure Humans Testosterone Prospective Studies Prospective cohort study Aged Urinary bladder business.industry Urinary Bladder Overactive Transurethral Resection of Prostate Middle Aged medicine.disease Urinary Bladder Neck Obstruction Urodynamics medicine.anatomical_structure Overactive bladder International Prostate Symptom Score business Prostatism |
| Zdroj: | BJU international. 101(12) |
| ISSN: | 1464-410X |
| Popis: | OBJECTIVES To determine the relationship between androgens, lower urinary tract symptoms (LUTS) and urodynamic variables of bladder outlet obstruction (BOO) in patients with LUTS/benign prostatic hyperplasia (BPH), as androgens are important in the pathogenesis of LUTS. PATIENTS AND METHODS Twenty-five men with symptomatic BPH were enrolled in the study and had a complete urodynamic investigation, establishing BOO. Age, prostate-specific antigen level, prostate volume and postvoid residual volume were recorded and the International Prostate Symptom Score (IPSS) was estimated. Detrusor pressure at maximum flow (PdetQmax), at urethral closure (PdetCl, the pressure at the end of urinary flow) and maximum detrusor pressure (Pdetmax) was recorded, while detrusor overactivity (DO) was noted when present. Blood samples were collected to measure total testosterone (T), and free T (FT) was calculated. Patients were grouped according to FT levels as low ( |
| Databáze: | OpenAIRE |
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