Computed Tomography as a Characterization Tool for Engineered Scaffolds with Biomedical Applications
| Autor: | Andrada Serafim, Horia Iovu, Izabela-Cristina Stancu, Elena Olăreț |
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| Rok vydání: | 2021 |
| Předmět: |
Technology
Structure analysis Computer science 3d model Computed tomography Review In situ visualization accurate morphometric characterization Field (computer science) 3D imaging medicine General Materials Science Microscopy QC120-168.85 medicine.diagnostic_test quantitative analysis QH201-278.5 computed tomography Engineering (General). Civil engineering (General) TK1-9971 Visualization Characterization (materials science) Descriptive and experimental mechanics Electrical engineering. Electronics. Nuclear engineering TA1-2040 Wall thickness Biomedical engineering biomaterials |
| Zdroj: | Materials Materials, Vol 14, Iss 6763, p 6763 (2021) |
| ISSN: | 1996-1944 |
| DOI: | 10.0223/v1 |
| Popis: | The ever-growing field of materials with applications in the biomedical field holds great promise regarding the design and fabrication of devices with specific characteristics, especially scaffolds with personalized geometry and architecture. The continuous technological development pushes the limits of innovation in obtaining adequate scaffolds and establishing their characteristics and performance. To this end, computed tomography (CT) proved to be a reliable, nondestructive, high-performance machine, enabling visualization and structure analysis at submicronic resolutions. CT allows both qualitative and quantitative data of the 3D model, offering an overall image of its specific architectural features and reliable numerical data for rigorous analyses. The precise engineering of scaffolds consists in the fabrication of objects with well-defined morphometric parameters (e.g., shape, porosity, wall thickness) and in their performance validation through thorough control over their behavior (in situ visualization, degradation, new tissue formation, wear, etc.). This review is focused on the use of CT in biomaterial science with the aim of qualitatively and quantitatively assessing the scaffolds’ features and monitoring their behavior following in vivo or in vitro experiments. Furthermore, the paper presents the benefits and limitations regarding the employment of this technique when engineering materials with applications in the biomedical field. |
| Databáze: | OpenAIRE |
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