Extracting novel antimicrobial emergence events from scientific literature and medical reports
| Autor: | Brooke Watson Madubuonwu, Allison M. White, Noam Ross, Melanie Kirshenbaum Lieberman, Erica Johnson, Samantha Maher, Emma Mendelsohn, Sonia Dattaray, Mushtaq Dualeh, Jacob Kotcher, Zach Matson, Cale Basaraba, Karissa Whiting, Nchedochukwu Ezeokoli, Peter Daszak, Carlos Zambrana-Torrelio |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Imipenem medicine.medical_specialty global health Scientific literature Biology Data Note Antimicrobial resistance 01 natural sciences General Biochemistry Genetics and Molecular Biology 010104 statistics & probability 03 medical and health sciences Antibiotic resistance Anti-Infective Agents Drug Resistance Bacterial medicine Global health Humans 0101 mathematics General Pharmacology Toxicology and Pharmaceutics Intensive care medicine Antibiotic Drugs Disease surveillance General Immunology and Microbiology Bacterial Infections Articles General Medicine Antimicrobial Anti-Bacterial Agents Klebsiella pneumoniae 030104 developmental biology open-access data medicine.drug |
| Zdroj: | F1000Research |
| ISSN: | 2046-1402 |
| DOI: | 10.12688/f1000research.26870.1 |
| Popis: | Despite considerable global surveillance of antimicrobial resistance (AMR), data on the global emergence of new resistance genotypes in bacteria has not been systematically compiled. We conducted a study of English-language scientific literature (2006-2017) and ProMED-mail disease surveillance reports (1994-2017) to identify global events of novel AMR emergence (first clinical reports of unique drug-bacteria resistance combinations). We screened 24,966 abstracts and reports, ultimately identifying 1,757 novel AMR emergence events from 268 peer-reviewed studies and 26 disease surveillance reports (294 total). Events were reported in 66 countries, with most events in the United States (152), China (128), and India (127). The most common bacteria demonstrating new resistance were Klebsiella pneumoniae (344) and Escherichia coli (218). Resistance was most common against antibiotic drugs imipenem (89 events), ciprofloxacin (84) and ceftazidime (83). We provide an open-access database of emergence events with standardized fields for bacterial species, drugs, location, and date. We discuss the impact of reporting and surveillance bias on database coverage, and we suggest guidelines for data analysis. This database may be broadly useful for understanding rates and patterns of AMR evolution, identifying global drivers and correlates, and targeting surveillance and interventions. |
| Databáze: | OpenAIRE |
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