Surface enhanced Raman spectroscopy of phenolic antioxidants: A systematic evaluation of ferulic acid, p-coumaric acid, caffeic acid and sinapic acid
| Autor: | Iris Aguilar-Hernández, Jens Petter Wold, Tzarara López-Luke, Nancy Ornelas-Soto, Nils Kristian Afseth, Flavio F. Contreras-Torres |
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| Rok vydání: | 2017 |
| Předmět: |
Analyte
Silver Ferulic acids Principal component analysis 02 engineering and technology Coumaric acid 01 natural sciences p-Coumaric acid Antioxidants Ferulic acid symbols.namesake chemistry.chemical_compound Caffeic acid Organic chemistry Colloids Phenolic antioxidant Spectroscopy Detection limit Chromatography Chemistry SERS 010401 analytical chemistry Sinapic acids Surface-enhanced Raman spectroscopy 021001 nanoscience & nanotechnology 0104 chemical sciences Caffeic acids 7 INGENIERÍA Y TECNOLOGÍA P-coumaric acid Light transmission Raman spectroscopy symbols 0210 nano-technology |
| Zdroj: | Vibrational Spectroscopy |
| ISSN: | 0924-2031 |
| DOI: | 10.1016/j.vibspec.2017.02.002 |
| Popis: | Surface-Enhanced Raman Spectroscopy (SERS) is a powerful surface-sensitive technique to study the vibrational properties of analytes at very low levels of concentration. In particular, detection of bioactive molecules, specifically antioxidants, is an area of interest to gain insights into the reproducible and quantitative SERS-determination. In this study, SERS measurements were systematically evaluated for ferulic acid, p-coumaric acid, caffeic acid and sinapic acid. The study objective in this research was to: 1) prepare and characterize SERS-active silver colloids; 2) cluster the as-obtained colloids through Principal Component Analysis on the basis of concentration and nanoparticle size; and 3) develop a highly sensitive SERS-based method for phenolic antioxidant detection. The reliability of the proposed method was demonstrated through detection of the phenolic antioxidants evaluated at low levels of concentration. In particular, sinapic acid was evaluated for the first time, with a limit of detection of 2.5 × 10−9 M. © 2017 The Authors |
| Databáze: | OpenAIRE |
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