Natural substrates of plant proteases: how can protease degradomics extend our knowledge?
| Autor: | Liana Tsiatsiani, Kris Gevaert, Frank Van Breusegem |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Proteomics
Proteasome Endopeptidase Complex Proteases Protease La Physiology Proteolysis medicine.medical_treatment Arabidopsis Plant Immunity Plant Science Computational biology Biology Genome Substrate Specificity Mitochondrial Proteins Genetics medicine Arabidopsis thaliana Subtilisins Plant Proteins Protease medicine.diagnostic_test Arabidopsis Proteins Abiotic stress fungi food and beverages Endopeptidase Clp Cell Biology General Medicine biology.organism_classification Mitochondria Enzyme Activation Cysteine Endopeptidases Protein Transport Biochemistry Metalloproteases Protein Processing Post-Translational |
| Zdroj: | Physiologia Plantarum. 145:28-40 |
| ISSN: | 0031-9317 |
| DOI: | 10.1111/j.1399-3054.2011.01534.x |
| Popis: | Despite the key role of proteolysis in various intensively studied biological processes, such as plant immunity, seed development and abiotic stress responses, our knowledge on the identity of natural protease substrates in plants remains scarce. In the genome of the model plant Arabidopsis thaliana, for instance, approximately 700 genes code for proteases. However, only a few natural substrates have been identified, mainly because of the previous lack of sensitive proteomics technologies enabling the identification of low abundant proteins, together with a delay in the implementation of these technologies in the field of plant research. Here, we review the current knowledge on the identity of natural plant protease substrates and describe recently established degradomics technologies that should allow proteome-wide studies of plant proteases in the near future. |
| Databáze: | OpenAIRE |
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