A General Carbonyl Alkylative Amination Process for Tertiary Amine Synthesis

Autor: Roopender Kumar, Nils Floden, William G. Whitehurst, Matthew Gaunt
Rok vydání: 2019
DOI: 10.26434/chemrxiv.10028504
Popis: We report a practical and general solution to this long-standing synthetic challenge can be accomplished by addition of alkyl radicals to all alkyl-iminium ions. The process is mediated by the action of visible light and a simple silane reducing agent, establishing a chain process that permits the combination of an extremely wide range of aldehydes and secondary amines with alkyl halides.
Databáze: OpenAIRE