Outcome after bilateral deep vein thrombosis

Autor: Fürbringer-Schwarz, Aline, Janscak, Marie, Jeanneret-Gris, Christina R
Přispěvatelé: University of Zurich, Jeanneret-Gris, Christina R
Rok vydání: 2022
Předmět:
Zdroj: Vasa. 51:372-376
ISSN: 1664-2872
0301-1526
DOI: 10.1024/0301-1526/a001030
Popis: Summary: Background: The aim of our study was to assess how often deep vein thrombosis (DVT) occurs bilaterally and if this has an impact on the recurrence rate of thromboembolic disease and on the occurrence of malignant tumors. Additionally, the occurrence of pulmonary embolism and mortality of patients was assessed. Patients and methods: For this observational study, we retrospectively screened all patient’s records for DVT, investigated between 2000 and 2017. 2409 patients with the diagnosis of DVT were found. The patients aged between 18 and 89 years old in 2017, received a follow-up questionnaire, asking for thromboembolic recurrence, malignant tumors and pulmonary embolism. 755 patients were included in the follow-up cohort (604 with unilateral, 151 with bilateral DVT). We performed nonparametric tests to assess two group analysis. Results: Bilateral DVT occurred in 19% of the patients in this cohort. Patients with bilateral DVT develop significantly more often cancer, either at the time of diagnosis or in the follow up, compared to patients with unilateral DVT (22.5% vs. 15.4%, p=0.036). They also endure significantly more often pulmonary embolism simultaneously (33.8% vs. 20.8%, p
Databáze: OpenAIRE