Risk factors of posthepatectomy liver failure for perihilar cholangiocarcinoma: Risk score and significance of future liver remnant volume-to-body weight ratio
| Autor: | Song C. Kim, Woohyung Lee, Jong W. Lee, Dae W. Hwang, Jae Hoon Lee, Jaewoo Kwon, Yejong Park, K.B. Song |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Multivariate analysis Single Center Gastroenterology chemistry.chemical_compound Risk Factors Internal medicine medicine Hepatectomy Humans Aged Retrospective Studies Framingham Risk Score Bile duct business.industry Incidence (epidemiology) Body Weight Liver failure Area under the curve General Medicine medicine.anatomical_structure Oncology chemistry Bile Duct Neoplasms Liver ROC Curve Surgery Female Bile Ducts business Indocyanine green Liver Failure Klatskin Tumor |
| Zdroj: | Journal of surgical oncologyREFERENCES. 122(3) |
| ISSN: | 1096-9098 |
| Popis: | BACKGROUND Surgery for perihilar cholangiocarcinoma (PHCC) is associated with high morbidity. This study aimed to investigate the clinical value of the future liver remnant volume-to-body weight (FLRV/BW) and propose a risk score for predicting the risk of patients with PHCC developing posthepatectomy liver failure (PHLF). METHODS This study included 348 patients who underwent major hepatectomy with bile duct resection for PHCC during 2008-2015 at a single center in Korea and they were retrospectively analyzed. RESULTS Clinically relevant PHLF was noted in 40 patients (11.4%). The area under the curve (AUC) for FLRV/BW was not significantly different from that for FLRV/total liver volume (P = .803) or indocyanine green clearance of the future liver remnant (P = .629) in terms of predicting PHLF. On multivariate analysis, predictors of PHLF (P |
| Databáze: | OpenAIRE |
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