Progressive multifocal leukoencephalopathy-remission with cytarabine
| Autor: | P. A. Daly, S. D. Gardner, Michael Hutchinson, T. O'Riordan, A. G. Shattock |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Microbiology (medical)
Pathology medicine.medical_specialty Intrathecal Drug Administration Schedule Leukoencephalopathy medicine Humans Rapidly progressive dementia medicine.diagnostic_test business.industry Progressive multifocal leukoencephalopathy Remission Induction Cytarabine Leukoencephalopathy Progressive Multifocal Complete remission Magnetic resonance imaging Middle Aged medicine.disease JC Virus Magnetic Resonance Imaging Lymphoma Infectious Diseases Injections Intravenous Female business medicine.drug |
| Zdroj: | Journal of Infection. 20:51-54 |
| ISSN: | 0163-4453 |
| DOI: | 10.1016/s0163-4453(90)92324-e |
| Popis: | A 51-year-old woman who was in complete remission from non-Hodgkin's lymphoma, developed a rapidly progressive dementia. Progressive multifocal leukoencephalopathy (PML) was diagnosed on the basis of a rising antibody titre to JC polyomavirus in cerebro-spinal fluid and serum and the presence of diffuse white matter changes on magnetic resonance imaging. She was treated initially with intravenous cytarabine and showed minimal improvement. Rapid improvement occurred when intrathecal cytarabine was added and the patient is in complete remission from both lymphoma and PML 20 months later. |
| Databáze: | OpenAIRE |
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