ULTRASTRUCTURAL CHANGES IN THE ADENOHYPOPHYSIS OF HYPOTHYROID RABBITS
| Autor: | C. L. Foster, B. A. Young, E. Cameron |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Pituitary gland Endocrinology Diabetes and Metabolism medicine.medical_treatment Biology Endoplasmic Reticulum Muscle hypertrophy Endocrinology Hypothyroidism Internal medicine medicine Animals Endoplasmic reticulum Thyroidectomy Hypertrophy Prolactin Microscopy Electron medicine.anatomical_structure Propylthiouracil Pituitary Gland Ultrastructure Female Rabbits medicine.drug |
| Zdroj: | Journal of Endocrinology. 44:273-277 |
| ISSN: | 1479-6805 0022-0795 |
| DOI: | 10.1677/joe.0.0440273 |
| Popis: | SUMMARY The ultrastructure of the adenohypophysis of the rabbit, after treatment with propylthiouracil, is described. All cells in the zona tuberalis and pars distalis proper, with the exception of the prolactin producing (type 1) and stellate cells (type 5), were affected. However, the only ones which presented some evidence of sequential changes were the type 4 cells. These became markedly degranulated and sometimes showed vesiculation of the cisternae of the granular endoplasmic reticulum, similar to that observed in the 'thyroidectomy' cells in some other species. Although changes occurred in the somatotrophs (type 2) and in the gonadotrophs (type 3) the evidence suggests that it is the type 4 cells which have a thyrotrophic function. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|