Depression treatment research in people with cancer does not reflect cancer prevalence: findings from a systematic review
| Autor: | Benjamin D. Bravery, Michael Murphy, Siobhan A. Loughnan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Evidence-based practice Population Antineoplastic Agents PsycINFO Treatment research 03 medical and health sciences 0302 clinical medicine Breast cancer Neoplasms Health care Medicine Humans 030212 general & internal medicine education Psychiatry Head and neck Cancer prevalence Aged Aged 80 and over education.field_of_study business.industry Depression Evidence-Based Nursing Middle Aged medicine.disease Antidepressive Agents Psychiatry and Mental health 030220 oncology & carcinogenesis Practice Guidelines as Topic Female business |
| Zdroj: | Evidence-based mental health. 23(4) |
| ISSN: | 1468-960X |
| Popis: | BackgroundOne in six people with cancer will develop depression at some point in their care. Untreated depression affects quality of life, cancer care satisfaction and healthcare expenditure. Treatments for this vulnerable heterogenous population should be evidence based and specific. A common sentiment is that psychiatric research does not reflect the prevalence of patients with cancer and comorbid depression and is biased towards certain cancers, but this has not been empirically shown.Study selection and analysisA systematic review of studies on psychological and pharmacological treatments for depression in people with cancer was conducted. Of 4621 papers identified from a search of PubMed and PsycINFO up to 27 June 2020, 84 met inclusion criteria (eg, adults with cancer; depression diagnosis; treatment study) and comprised 6048 participants with depression with cancer.FindingsCancer types are not proportionally represented in depression research in accordance with their incidence. Breast cancer is over-represented (relative frequency in research 49.3%, but 11.7% of global cancer). Cancers of the head and neck and bone and soft tissue were close to parity. All other cancers are under-represented. Representativeness varied 40-fold across different cancers.ConclusionsThe evidence base for depression treatments is dominated by a single cancer. Given heterogeneity in cancer populations (eg, stage of illness; psychological impact; cancer treatments), it is possible that depression treatments may not have the same benefits and harms across all cancers, impeding the ability to offer people with different cancers the best depression treatment. While the dominant opinion within this research field is that a cancer bias exists, this is the first study to demonstrate as such. |
| Databáze: | OpenAIRE |
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