Asymptomatic urinary tract infections and associated risk factors in Pakistani Muslim type 2 diabetic patients
| Autor: | Amna Riaz, Syed Abbas Raza, Ibrar Ahmed, Faisal Masood Qureshi, Azizul Hasan Aamir, Umar Yousuf Raja, Tahir Ghaffar, Ali Asghar, Irshad Ahmed Khosa, Jaffer Bin Baqar, Jamal Zafar, Mohammad Imtiaz Hasan, Mahwish Raza, Saeed Ahmed Mahar, Jahanzeb K. khan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Glycosuria medicine.medical_specialty Type II diabetes mellitus Adolescent Urinary system 030209 endocrinology & metabolism Infectious and parasitic diseases RC109-216 Urine Urinalysis Islam Asymptomatic Young Adult 03 medical and health sciences Sex Factors 0302 clinical medicine Risk Factors Pakistani Muslim population Diabetes mellitus Internal medicine Escherichia coli Prevalence medicine Humans Pakistan 030212 general & internal medicine Risk factor Asymptomatic Infections Escherichia coli Infections Aged business.industry Research Age Factors Type 2 Diabetes Mellitus Middle Aged Urinary tract infections medicine.disease Cross-Sectional Studies Infectious Diseases Diabetes Mellitus Type 2 Female medicine.symptom business Body mass index |
| Zdroj: | BMC Infectious Diseases BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-6 (2021) |
| ISSN: | 1471-2334 |
| DOI: | 10.1186/s12879-021-06106-7 |
| Popis: | Background One of the leading long-term complications of type 2 diabetes mellitus (T2DM) includes renal dysfunction and urinary tract infections (UTI) which are considered to be prevalent in uncontrolled diabetes. Moreover, physiological factors like age, gender, duration of diabetes, other diabetic complications like neuropathy, autonomic neuropathy and glycosuria are also considered as predisposing factors for increased prevalence of UTI in diabetes which can be symptomatic or asymptomatic. Methods This was a cross-sectional, multi-centre study including diabetic patients from 12 clinical sites spread across major cities of Pakistan. The inclusion criteria were adult Pakistani population of age between 18 to 75 years both genders and suffering from T2DM irrespective of duration. A detailed clinical history of the past 3 months was recorded and, biochemical investigations of blood samples were conducted. Urine culture analysis performed identified the type of pathogen present and was done only for asymptomatic patients. Results A total of 745 type 2 diabetic patients were initially screened, out of 545 patients considered for final analysis 501 (91.92%) were negative and the rest 44 (8.08%) had positive urine culture. Female gender had a significantly higher proportion of positive urine culture (77.27%, p-valueEscherichia coli was detected in most of the positive samples (52.3%). All bacterial samples were found resistant to Ciprofloxacin. Conclusion Diabetic Pakistani muslim female patients are identified to be at high risk of suffering from asymptomatic UTI and age more than 40 years is an important risk factor. Escherichia coli was the most common causative organism among people living in this geographical area. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink