Typical rise and fall of troponin in (peri-procedural) myocardial infarction : A systematic review
| Autor: | Wilton A. van Klei, Marjolein F Looije, Bas van Zaane, Dianne E. C. van Beek, Linda M. Peelen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Systematic Reviews Peri Coronary artery bypass grafting macromolecular substances 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Journal Article Myocardial infarction cardiovascular diseases biology business.industry Electrocardiography in myocardial infarction 030208 emergency & critical care medicine musculoskeletal system medicine.disease Troponin Reperfusion cardiovascular system Cardiology biology.protein Systematic review Cardiology and Cardiovascular Medicine business |
| Zdroj: | World Journal of Cardiology, 8(3), 293. Baishideng Publishing Group |
| ISSN: | 1949-8462 |
| Popis: | AIM: To identify the typical shape of the rise and fall curve of troponin (Tn) following the different types of myocardial infarction (MI). METHODS: We conducted a systematic search in PubMed and Embase including all studies which focused on the kinetics of Tn in MI type 1, type 4 and type 5. Tn levels were standardized using the 99(th) percentile, a pooled mean with 95%CI was calculated from the weighted means for each time point until 72 h. RESULTS: A total of 34 of the 2528 studies identified in the systematic search were included. The maximum peak level of the Tn was seen after 6 h after successful reperfusion of an acute MI, after 12 h for type 1 MI and after 72 h for type 5 MI. In type 1 MI there were additional smaller peaks at 1 h and at 24 h. After successful reperfusion of an acute MI there was a second peak at 24 h. There was not enough data available to analyze the Tn release after MI associated with percutaneous coronary intervention (type 4). CONCLUSION: The typical rise and fall of Tn is different for type 1 MI, successful reperfusion of an acute MI and type 5 MI, with different timing of the peak levels and different slopes of the fall phase. |
| Databáze: | OpenAIRE |
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