The Short-Term Effect of Eugenol on the Prevention of Experimentally Induced Myringosclerosis in a Rat Model
| Autor: | Oguz Kadir Egilmez, Ebru Mihriban Güven, Halil Elden, Mehmet Güven, Sena Genç Elden, Özcan Budak, Hüseyin Çakıroğlu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Lamina propria
Myringosclerosis business.industry Tympanic membrane medicine.medical_treatment Rat model Pharmacology medicine.disease myringosclerosis rats Eugenol Myringotomy chemistry.chemical_compound antioxidants medicine.anatomical_structure chemistry Fibrosis medicine Term effect business eugenol Saline Original Investigation animal experimentation |
| Zdroj: | Turkish Archives of Otorhinolaryngology |
| ISSN: | 1303-6289 0304-4793 |
| Popis: | Objective: The aim of our study was to assess the possible short-term effects of topical and oral eugenol on the suppression of experimentally developed myringosclerosis (MS). Methods: Four groups of seven male Wistar albino rats were used in the study. The tympanic membranes (TMs) of all subjects were myringotomized, and group 1 was given no treatment (as control group), group 2 received saline, group 3 had received topical eugenol and group 4 received oral eugenol. Results: In macroscopic evaluation the control and saline groups showed much more MS compared to the topical and oral eugenol groups which had statistically significantly less changes (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|