Indirect fabrication of versatile 3D microfluidic device by a rotating plate combined 3D printing system
Autor: | Soo-Young Park, Dong-Woo Cho, Do Jin Im, Byoung Soo Kim, Steve Park, Jin-Oh Kim, Dong-Hyeon Ko, Dong-Heon Ha, Dong-Pyo Kim |
---|---|
Rok vydání: | 2018 |
Předmět: |
Chemical process
Fabrication Materials science business.industry General Chemical Engineering Microfluidics Micromixer 3D printing Nanotechnology 02 engineering and technology General Chemistry Substrate (printing) 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences chemistry.chemical_compound chemistry UV curing Fluoropolymer 0210 nano-technology business |
Zdroj: | RSC Advances. 8:37693-37699 |
ISSN: | 2046-2069 |
DOI: | 10.1039/c8ra08465c |
Popis: | In the past decade, 3D-printing technology has been applied in the field of microfluidics to fabricate microfluidic devices for wide-ranging areas of study including chemistry, biology, medicine, and others. However, these methods face several limitations such as insufficient resolution and long fabrication time. In this study, versatile microfluidic devices with different functions were indirectly fabricated by a rapid sacrificial template printing process using a photocurable fluoropolymer with chemical durability. The Pluronic® F127 hydrogel as a sacrificial template was rapidly patterned on substrates by a non-lithographic printing process using a computer-controlled 3D-printing system. Viscous fluoropolymer was cast on the non-deformable template that was consequently removed by applying heat and negative pressure after UV curing. The chemical-resistant and transparent microchannels were oblate-hemispherical on the cross section. They were tested by performing a heterogeneous catalytic reaction as well as a photochemical reaction. The microchannels with controlled heights were devised to induce convection for functioning as a micromixer with asymmetric flows. Moreover, upon printing the Pluronic® F127 on both sides of the PFPE (perfluoropolyether-urethane dimethacrylate) membrane substrate, the 3D hybrid microfluidic device was embedded with a permeable membrane between the lower and upper channels, which is useful for gas-liquid chemical processes. |
Databáze: | OpenAIRE |
Externí odkaz: |