Limitations in Predicting the Space Radiation Health Risk for Exploration Astronauts

Autor: Rebecca S. Blue, Helmut G. Katzgraber, Kathleen H. Rubins, Ann R. Kennedy, Serena M. Auñón-Chancellor, Keith A. Cengel, Jeffery C. Chancellor
Rok vydání: 2017
Předmět:
0301 basic medicine
Physics and Astronomy (miscellaneous)
Computer science
lcsh:Biotechnology
Materials Science (miscellaneous)
Medicine (miscellaneous)
FOS: Physical sciences
Review Article
Biochemistry
Genetics and Molecular Biology (miscellaneous)

lcsh:Physiology
03 medical and health sciences
0302 clinical medicine
Physics - Space Physics
lcsh:TP248.13-248.65
Physics - Biological Physics
Health risk
Aerospace
lcsh:QP1-981
business.industry
Human spaceflight
Space radiation
Physics - Medical Physics
Agricultural and Biological Sciences (miscellaneous)
Space Physics (physics.space-ph)
Radiation exposure
030104 developmental biology
Risk analysis (engineering)
13. Climate action
Space and Planetary Science
Biological Physics (physics.bio-ph)
030220 oncology & carcinogenesis
Risk IT
Medical Physics (physics.med-ph)
business
Interplanetary spaceflight
Zdroj: NPJ Microgravity
npj Microgravity, Vol 4, Iss 1, Pp 1-11 (2018)
DOI: 10.48550/arxiv.1710.07311
Popis: Despite years of research, understanding of the space radiation environment and the risk it poses to long-duration astronauts remains limited. There is a disparity between research results and observed empirical effects seen in human astronaut crews, likely due to the numerous factors that limit terrestrial simulation of the complex space environment and extrapolation of human clinical consequences from varied animal models. Given the intended future of human spaceflight, with efforts now to rapidly expand capabilities for human missions to the moon and Mars, there is a pressing need to improve upon the understanding of the space radiation risk, predict likely clinical outcomes of interplanetary radiation exposure, and develop appropriate and effective mitigation strategies for future missions. To achieve this goal, the space radiation and aerospace community must recognize the historical limitations of radiation research and how such limitations could be addressed in future research endeavors. We have sought to highlight the numerous factors that limit understanding of the risk of space radiation for human crews and to identify ways in which these limitations could be addressed for improved understanding and appropriate risk posture regarding future human spaceflight.
Comment: Accepted for publication by Nature Microgravity (2018)
Databáze: OpenAIRE