Benzodiazepine dependence in subjects with alcohol use disorders: what prevalence?
| Autor: | Marie Grall-Bronnec, Samuel Bulteau, M. L. Pinot, P. Chauvin-Grelier, A. Morel, Pascale Jolliet, L. Gailledrat, Caroline Victorri-Vigneau |
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| Přispěvatelé: | Service de radiothérapie, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN), French Society for Biological Psychiatry and Neuropsychopharmacology, Partenaires INRAE, Centre hospitalier universitaire de Nantes (CHU Nantes), Service de Pharmacologie Clinique [CHU Nantes] (SPC), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Cross-sectional study medicine.drug_class Substance-Related Disorders [SDV]Life Sciences [q-bio] media_common.quotation_subject Benzodiazepine dependence France/epidemiology Abuse 03 medical and health sciences Benzodiazepines 0302 clinical medicine Surveys and Questionnaires Benzodiazepines/administration & dosage/*adverse effects mental disorders Ambulatory Care/methods medicine Ambulatory Care Prevalence Humans Pharmacology (medical) 030212 general & internal medicine Psychiatry media_common Benzodiazepine substance use disorder alcohol business.industry Addiction dependence General Medicine Middle Aged Alcohol-Related Disorders/epidemiology/*rehabilitation medicine.disease ArtThese 3. Good health Substance abuse Cross-Sectional Studies Substance-Related Disorders/*epidemiology Female France Substance Abuse Treatment Centers benzodiazepine business Alcohol-Related Disorders 030217 neurology & neurosurgery Specific population |
| Zdroj: | Expert opinion on drug safety Expert opinion on drug safety, 2016, 15 (10), pp.1313-1319. ⟨10.1080/14740338.2016.1221922⟩ |
| ISSN: | 1744-764X |
| DOI: | 10.1080/14740338.2016.1221922⟩ |
| Popis: | International audience; OBJECTIVE: To our knowledge, no studies have been conducted in France on benzodiazepine (BZD) dependence among outpatients with alcohol use disorders (AUD). Some international studies have been conducted on the consumption of BZD in this specific population, but the comparisons among them are difficult. We aimed to assess the current prevalence of probable benzodiazepine and BZD-like hypnotics (Z-drugs) dependence among outpatients seeking treatment for AUD. METHODS: Participants were patients seeking treatment for AUD for the first time or repeating treatment after more than twelve months. Recruitment took place in seven addiction centres between January and December 2013 in the Nantes region (France). BZD/Z-drug dependence was assessed according to the DSM-IV diagnostic criteria for dependence. This information was gathered through a self-report questionnaire. RESULTS: Among the 1005 patients included in this study, 413 were BZD/Z-drug users (41.1%). Among the 413 patients, 217 were probably dependent on at least one substance, which represents 21.6% of the total population and 52.5% of BZD/Z-drug users. CONCLUSION: BZD/Z-drug dependence represents a public health concern. Prescribers should take the risks into account and keep treatment courses to a minimum. |
| Databáze: | OpenAIRE |
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