Comprehensive review on Caelsalpinioideae lectins: From purification to biological activities

Autor: Vanir Reis Pinto-Junior, Messias Vital Oliveira, Benildo Sousa Cavada, Alfa Umaro Bari, Vinicius Jose Da Silva Osterne, Lara Dias Lima, Kyria S. Nascimento, Claudia Figueiredo Lossio, Claudio Henrique Dahne Souza-Filho, Mayara Torquato Lima Silva
Rok vydání: 2020
Předmět:
BIOCHEMICAL-CHARACTERIZATION
Caesalpinioideae
Antifungal Agents
Subfamily
Future studies
Anti-Inflammatory Agents
Molecular Conformation
Antineoplastic Agents
02 engineering and technology
Plant Lectins
Biology
Antiviral Agents
Biochemistry
03 medical and health sciences
Protein Domains
Structural Biology
Genus
Lectins
CRYSTAL-STRUCTURE
Amino Acid Sequence
Molecular Biology
Phylogeny
030304 developmental biology
MILLIGRAM QUANTITIES
CARBOHYDRATE-BINDING
0303 health sciences
GRIFFONIA-SIMPLICIFOLIA
BANDEIRAEA-SIMPLICIFOLIA SEEDS
INITIAL ADHESION
Bauhinia
GALACTOSE-SPECIFIC LECTIN
Binding properties
AFFINITY-CHROMATOGRAPHY
Fabaceae
General Medicine
021001 nanoscience & nanotechnology
biology.organism_classification
Anti-Bacterial Agents
Chemistry
Metals
Leguminosae
BAUHINIA-PURPUREA LECTIN
0210 nano-technology
Zdroj: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN: 0141-8130
1879-0003
DOI: 10.1016/j.ijbiomac.2020.06.161
Popis: Lectins are a class of proteins with specific and reversible carbohydrate binding properties. Plant lectins constitute the group of these proteins most studied, placing emphasis on the legume family. The Caesalpinioideae subfamily is part of Leguminosae and second only to Papilionoideae with more published works on lectins. Classically, Caesalpinioideae is formed by 171 genera and 2250 species. It presents 13 genera with reports of lectins, featuring the Bauhinia genus with the greatest number of species having purified and characterized lectins. Comparing genera, the lectins in this subfamily do not have similar physicochemical or structural properties. Collectively, however, antibacterial, antiviral, and anticancer activities have been reported, as well as applications as biosensors and biomarkers. This review aims to summarize the available data on purified lectins from species of the Caesalpinioideae subfamily, demonstrating the characteristics of these molecules and the potential for their application in future studies of new lectins, as well as of application in several areas.
Databáze: OpenAIRE
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