Gallium scintigraphy in Hansen's disease
| Autor: | Maria Cecilia M. Rivitti, Elaine Bortoleti de Araújo, Hateme Bouladour, Edwaldo E. Camargo, Leontina Margarido Tedesco-Marchesi, F. J. H. N. Braga, Pierre Galle |
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| Rok vydání: | 1991 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty chemistry.chemical_element Gallium Radioisotopes Disease Technetium Tc 99m Medronate Scintigraphy Bone and Bones Entire skin Leprosy medicine Humans Radiology Nuclear Medicine and imaging Gallium Radionuclide Imaging Lung Skin integumentary system medicine.diagnostic_test business.industry General Medicine medicine.disease chemistry Liver Homogeneous Technetium Tc 99m Sulfur Colloid Organ involvement Histopathology Female business Spleen |
| Zdroj: | European journal of nuclear medicine. 18(11) |
| ISSN: | 0340-6997 |
| Popis: | Gallium 67 imaging was used in 12 patients with documented Hansen's disease undergoing treatment or not, in an attempt to determine the pattern of the disease. Diagnosis was confirmed by histopathology in all patients. The Mitsuda reaction was seen in all patients. Specific nuclear studies were performed when needed to evaluate particular organs better. Gallium 67 images show homogeneous, diffuse and moderate accumulation over the entire skin surface (except for the face) of untreated patients with multibacillary disease. The facial skin in these cases presented homogeneous, diffuse but very marked uptake of gallium. Internal organ involvement was variable. There was a very good correlation among clinical, scintigraphic, immunological and histopathological data. The pattern of the body skin (“skin outlining”) and facial skin (“beard distribution”) may be distinct for untreated patients with multibacillary leprosy. |
| Databáze: | OpenAIRE |
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