Older age is a risk factor for inadequate energy intake during acute, severe IBD and is associated with shorter time to relapse
| Autor: | Ann-Sofie Backman, Katja A Kulmala, Sara Andersson, Charlotte R H Hedin, Michael Eberhardson, Jan Björk, Francesca Bresso |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry Gastroenterology Time to relapse macromolecular substances Inflammatory Bowel Diseases medicine.disease digestive system Inflammatory bowel disease digestive system diseases 03 medical and health sciences 0302 clinical medicine Recurrence Risk Factors 030220 oncology & carcinogenesis Internal medicine Humans Medicine 030211 gastroenterology & hepatology Risk factor Energy Intake business Real world data Aged Retrospective Studies |
| Zdroj: | Scandinavian Journal of Gastroenterology. 55:1185-1192 |
| ISSN: | 1502-7708 0036-5521 |
| DOI: | 10.1080/00365521.2020.1818119 |
| Popis: | Effects of nutritional intake on inflammatory bowel disease (IBD) flare resolution are unknown. We hypothesised that nutritional factors during hospitalisation for acute severe IBD are associated with risk of subsequent relapse. We also studied risk factors for inadequate energy intake.Patients admitted to the Karolinska Hospital Gastroenterology ward with IBD flare during 2015-2016 were retrospectively identified. In total, 91 patients were included. Data on nutrition, disease factors, inflammatory markers, and daily energy requirement were extracted. Requirement of new systemic steroid prescription, intensification of biological therapy, readmission, surgery, and calprotectin level were individually used as proxies for disease relapse. Follow-up was one year after discharge. Adjustments for age and sex were made where appropriate.Overall, 19%, 31%, and 45% of patients had days with energy intake30,50, and70% of calculated requirement. Older age was associated with a higher number of days with energy intake30,50, and70% of calculated requirement (regression coefficient 0.03, 0.04, 0.06 respectively,Older age is a predictor of inadequate energy intake during hospitalisation for acute severe IBD. Inadequate energy intake adjusted for age and sex during IBD flare was better predictor of time to the next steroid-requiring relapse than inflammatory markers. |
| Databáze: | OpenAIRE |
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