Indicators of long chain polyunsaturated fatty acid status of exclusively breastfed infants at delivery and after 20–22 days

Autor: H.J. Nijeboer, E. R. Boersma, Pieter J. Offringa, C.M. van Beusekom, C.N. van der Veere, A.J. Luteyn, Frits A. J. Muskiet
Přispěvatelé: Faculteit Medische Wetenschappen/UMCG
Rok vydání: 1993
Předmět:
medicine.medical_specialty
Erythrocytes
SPLIT INJECTION
ALPHA-FETOPROTEIN
Breast milk
Umbilical cord
chemistry.chemical_compound
LONG CHAIN POLYUNSATURATED FATTY ACIDS
PHOSPHATIDYLCHOLINE
Internal medicine
medicine
Humans
HUMAN MILK
chemistry.chemical_classification
PLASMA
Milk
Human
Cholesterol
CHOLESTEROL
Infant
Newborn
food and beverages
Obstetrics and Gynecology
METHYL-ESTERS
Delivery
Obstetric
Fetal Blood
eye diseases
Red blood cell
Breast Feeding
Endocrinology
medicine.anatomical_structure
Biochemistry
chemistry
PLASMA CHOLESTEROL ESTERS
Cord blood
Pediatrics
Perinatology and Child Health
CAPILLARY GAS-CHROMATOGRAPHY
Fatty Acids
Unsaturated
Female
lipids (amino acids
peptides
and proteins)
Cholesterol Esters
sense organs
MEMBRANE
Alpha-fetoprotein
LIPID-COMPOSITION
Breast feeding
NEWBORN
Polyunsaturated fatty acid
Zdroj: Early Human Development, 32(2-3), 207-218. ELSEVIER IRELAND LTD
ISSN: 0378-3782
DOI: 10.1016/0378-3782(93)90013-k
Popis: The fatty acid composition of plasma cholesterol esters (CE), erythrocytes (RBC) and mature milk from seven lactating /women and their exclusively breastfed newborns, living on Dominica, were studied. Blood samples were taken from umbilical cord and mother at birth. A sample of breastmilk was collected on day 20-22 postpartum, together with a blood sample from the baby. At birth, cord blood plasma CE and RBC total long chain polyunsaturated fatty acid (LC-PUFA) contents were higher, and linoleic (18:2c,omega6) and alpha-linolenic (18:3c,omega3) acid contents lower, than in corresponding maternal compartments. Cord blood RBC LC-PUFA omega3 content was lower and LC-PUFA omega6 content higher than in maternal RBC. After birth, feeding with human milk led to a drop in LC-PUFA content in the plasma CE fraction, whereas RBC LC-PUFA content remained virtually constant. Current understanding of the origin and relative affinity of fatty acids incorporated in plasma CE and RBC suggests that RBC LC-PUFA content is a more reliable parameter for LC-PUFA status than plasma CE LC-PUFA content. The RBC LC-PUFA data suggest therefore that at birth the newborn has a lower LC-PUFA omega3 status than the mother, and that this does not change during three weeks of exclusive breastfeeding.
Databáze: OpenAIRE
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