The volcano mouse Neotomodon alstoni of central Mexico, a biological model in the study of breeding, obesity and circadian rhythms
| Autor: | Manuel Miranda-Anaya, Moisés Pérez-Mendoza, Cinthia Juárez-Tapia, Agustín Carmona-Castro |
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| Rok vydání: | 2018 |
| Předmět: |
Food intake
Mexican volcano mouse Zoology 030209 endocrinology & metabolism Rodentia Biology Neuroendocrinology Breeding Models Biological 03 medical and health sciences 0302 clinical medicine Endocrinology medicine Animals Circadian rhythm Obesity Mexico 030304 developmental biology 0303 health sciences Behavior Animal Biological modeling Neotomodon biology.organism_classification medicine.disease Circadian Rhythm Animal Science and Zoology Paternal care |
| Zdroj: | General and comparative endocrinology. 273 |
| ISSN: | 1095-6840 |
| Popis: | The "Mexican volcano mouse" Neotomodon alstoni, is endemic of the Transverse Neovolcanic Ridge in central Mexico. It is considered as least concern species and has been studied as a potential laboratory model from different perspectives. Two lines of research in neuroendocrinology have been addressed: reproduction and parental care, particularly focused on paternal attention and the influence of testosterone, and studies on physiology and behavior of circadian rhythms, focused on the circadian biology of the species, its circadian locomotor activity and daily neuroendocrine regulation of metabolic parameters related to energy balance. Some mice, when captive, spontaneously develop obesity, which allows for comparisons between lean and obese mice of daily changes in neuronal and metabolic parameters associated with changes in food intake and locomotor activity. This review includes studies that consider this species an attractive animal model where the alteration of circadian rhythms influences the pathogenesis of obesity, specifically with the basic regulation of food intake and metabolism and differences related to sex. This study can be considered as a reference to the comparative animal physiology among rodents. |
| Databáze: | OpenAIRE |
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