Expression of alpha tubulin during the dimorphic transition of Paracoccidioides brasiliensis

Autor:	Rosália Santos Amorim Jesuino, S. M. S. Izacc, C. M. A. Soares, W. P. Silva, Maria Sueli Soares Felipe, Renata de Bastos Ascenço Soares
Rok vydání:	2002
Předmět:	Gene isoform Paracoccidioides brasiliensis Transition (genetics) biology Mycelium Paracoccidioides macromolecular substances General Medicine Fungus biology.organism_classification Yeast Cell biology Microbiology Infectious Diseases Tubulin Gene expression biology.protein Protein Isoforms
Zdroj:	Medical mycology. 39(5)
ISSN:	1369-3786
Popis:	In this study we analyzed the expression of (alpha-tubulin during the dimorphic transition of the human-pathogenic fungus Paracoccidioides brasiliensis. The alpha-tubulin from P. brasiliensis was recognized by a commercially available anti-tubulin antibody and was developmentally regulated during the dimorphic form transition. We detected at least two alpha-tubulin isoforms in the mycelial state and only one isoform in the yeast forms. This finding suggests specific roles for the alpha-tubulin isoforms in P. brasiliensis's yeast and mycelial forms.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a42b90267db14bebd116b73206682f78 https://pubmed.ncbi.nlm.nih.gov/12054057 Zobrazit plný text záznamu