Molecular Genetic Polymorphism of Androgen Receptor (AR) Gene in African Populations of Hadza and Datoga

Autor: D V, Shibalev, V A, Vasil'ev, O E, Lazebnyi, E M, Suchodolskaya, A M, Kulikov, D A, Dronova, M L, Butovskaya, A P, Ryskov
Rok vydání: 2013
Předmět:
Zdroj: Генетика. 49:1440-1443
ISSN: 0016-6758
DOI: 10.7868/s0016675813120114
Popis: The molecular genetic analysis of the polymorphic variants of the CAG repeat-containing locus of the andro- gen receptor (AR) gene was performed in the populations of Hadza and Datoga. Allele frequency distribution patterns were established. Alleles containing 20-25 repeats were the most abundant in both populations were the. The populations studied were compared with Asians (Han), white Americans, and Africans (Ariaal). Sta- tistically significant difference between populations of Hadza and Datoga in the distribution of the AR allelic variants was demonstrated.
Databáze: OpenAIRE