Is there an estrogenic component in the metabolic syndrome?
| Autor: | S. Starcke, Günter Vollmer |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class business.industry Endocrinology Diabetes and Metabolism Insulin medicine.medical_treatment Leptin Clinical nutrition medicine.disease Bioinformatics Obesity Human genetics Article chemistry.chemical_compound Endocrinology chemistry Estrogen Internal medicine Genetics medicine Phytoestrogens Metabolic syndrome business |
| Zdroj: | Genesnutrition. 1(3-4) |
| ISSN: | 1555-8932 |
| Popis: | One of the major upcoming concerns leading to health related problems in the industrialized societies is the metabolic syndrome which is characterized by central obesity, hypertension, raised fasting glucose and triglyceride levels. The focus of this review is on a potential estrogenic linkage between the metabolic mechanisms involved into the development of this disease cluster and specific estrogen related regulatory pattern. The candidate molecules for this link are insulin and insulin-like growthfactor, C-reactive protein, peroxisome-proliferation-activatingreceptorgamma, and leptin which all seem to interact with each other and show a responsiveness to changing estrogen levels. From this perspective they might also represent target molecules for a phytochemical intervention with phytoestrogens. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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