Widespread detection of highly pathogenic H5 influenza viruses in wild birds from the Pacific Flyway of the United States
| Autor: | Hon S. Ip, John A. Baroch, Joan W. Bennett, J. Sengl, Mary Lea Killian, D. Kraege, S. Stopak, Tom Gidlewski, Robert J. Dusek, Ryan S. Miller, Crow White, Shannon C. Chandler, Paul DeBruyn, Brandon S. Schmit, Elisabeth L. Rowan, Sarah N. Bevins, C. Gillin, Thomas J. DeLiberto, K. G Mansfield, M. J. Grady, Barbara Bodenstein, Jonathan M. Sleeman, Erica Spackman, Caroline Brady, Mia Kim Torchetti, B. Thomas, M. L. Drew, B. Zscheile |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Canada Lineage (evolution) Animals Wild medicine.disease_cause Poultry Article Disease Outbreaks Birds 03 medical and health sciences Flyway Reassortant Viruses Influenza A virus medicine Waterfowl Animals Clade Poultry Diseases Multidisciplinary Influenza A Virus H5N1 Subtype biology biology.organism_classification Virology United States Influenza A virus subtype H5N1 030104 developmental biology Influenza in Birds North America Taxonomy (biology) Influenza A Virus H5N2 Subtype |
| Zdroj: | Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/srep28980 |
| Popis: | A novel highly pathogenic avian influenza virus belonging to the H5 clade 2.3.4.4 variant viruses was detected in North America in late 2014. Motivated by the identification of these viruses in domestic poultry in Canada, an intensive study was initiated to conduct highly pathogenic avian influenza surveillance in wild birds in the Pacific Flyway of the United States. A total of 4,729 hunter-harvested wild birds were sampled and highly pathogenic avian influenza virus was detected in 1.3% (n = 63). Three H5 clade 2.3.4.4 subtypes were isolated from wild birds, H5N2, H5N8, and H5N1, representing the wholly Eurasian lineage H5N8 and two novel reassortant viruses. Testing of 150 additional wild birds during avian morbidity and mortality investigations in Washington yielded 10 (6.7%) additional highly pathogenic avian influenza isolates (H5N8 = 3 and H5N2 = 7). The geographically widespread detection of these viruses in apparently healthy wild waterfowl suggest that the H5 clade 2.3.4.4 variant viruses may behave similarly in this taxonomic group whereby many waterfowl species are susceptible to infection but do not demonstrate obvious clinical disease. Despite these findings in wild waterfowl, mortality has been documented for some wild bird species and losses in US domestic poultry during the first half of 2015 were unprecedented. |
| Databáze: | OpenAIRE |
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