Histomorphometric analysis of poly-L/D-lactide 96/4 sutures in the gastrocnemius tendon of rabbits
| Autor: | Pertti Törmälä, Nureddin Ashammakhi, Jarmo Kangas, Timo Waris, Jorma Ryhänen, Juhana Leppilahti, Ari Pajala, Satu Länsman |
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| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Polyesters 0206 medical engineering 030232 urology & nephrology Biomedical Engineering Medicine (miscellaneous) Bioengineering 02 engineering and technology Fibrous tissue Fibrous capsule Biomaterials Tendons 03 medical and health sciences 0302 clinical medicine Suture (anatomy) medicine Animals Achilles tendon Sutures business.industry Capsule General Medicine Anatomy 020601 biomedical engineering Tendon Surgery medicine.anatomical_structure Poly-L-D-lactide Gastrocnemius tendon Rabbits business |
| Zdroj: | Europe PubMed Central |
| ISSN: | 0391-3988 |
| Popis: | Background Common Achilles tendon ruptures are not usually fixed by bioabsorbable sutures due to limitations in their strength retention properties. Modern technology has made it possible to develop bioabsorbable sutures with prolonged strength retention. Aims To evaluate histologically tissue reactions of poly-L/D-lactide (PLDLA) sutures implanted in Achilles tendon of rabbits. Material and Methods Fifteen rabbits were evaluated at 2, 6 and 12 weeks postoperatively, with five rabbits in each follow-up group. PLDLA monofilament sutures were implanted into the medial gastrocnemius tendon. Polyglyconate monofilament sutures with similar diameter (Maxon® 4–0, Cyanamid of Great Britain Ltd., Gosport, UK) were implanted in the contralateral gastrocnemius tendon. The histology was studied in hard-resin embedded samples. The thickness of the formed fibrous tissue capsule was determined histomorphometrically. Results PLDLA led to formation of significantly thinner fibrous tissue capsule than Maxon® sutures of the same diameter. Median thickness (PLDLA vs. Maxon®) at two weeks was 5.26 vs. 13.22μm, at six weeks 11.66 vs. 80.97μm, and at 12 weeks 10.63 vs. 17.59μm (pConclusions During the 12 week follow-up period, PLDLA sutures implanted intratendineously formed thinner fibrous capsule than Maxon® sutures of the same diameter. The suture materials were not totally absorbed by 12 weeks. |
| Databáze: | OpenAIRE |
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