Long-term effects of a linoleic acid-enriched diet, changes in body weight and alcohol consumption on serum total and HDL-cholesterol
| Autor: | E. A. van der Velde, H.A. van der Voort, Jacques D. Barth, H.J.M. Kempen, N. Kempen-Voogd, A. C. Arntzenius, Daan Kromhout |
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| Rok vydání: | 1987 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Alcohol Drinking Linoleic acid Alcohol Body weight Angina Pectoris Linoleic Acid chemistry.chemical_compound Total cholesterol Internal medicine medicine Humans Total fat Cholesterol business.industry Body Weight Cholesterol HDL Fatty Acids nutritional and metabolic diseases Middle Aged Diet Endocrinology chemistry Biochemistry Linoleic Acids Lower total cholesterol lipids (amino acids peptides and proteins) Female Cholesterol Esters Cardiology and Cardiovascular Medicine business Alcohol consumption |
| Zdroj: | Atherosclerosis. 66(1-2) |
| ISSN: | 0021-9150 |
| Popis: | Investigations on diet, body weight, and lipoproteins were carried out in 28 patients with stable angina pectoris. They consumed a linoleic acid-enriched diet (P/S ratio = 2) for a period of 2 years. The total fat content remained constant before and during intervention, contributing 34% to energy intake. During intervention serum total cholesterol and the total/HDL cholesterol ratio decreased significantly, but HDL cholesterol did not change. Changes in body weight were significantly inversely related to changes in HDL cholesterol and positively to the total/HDL cholesterol ratio. Changes in alcohol intake were significantly positively related to both total and HDL cholesterol but unrelated to the total/HDL cholesterol ratio. From the results of this long-term study it can be concluded that a moderate fat diet with a P/S ratio of 2 can lower total cholesterol effectively without affecting HDL cholesterol. |
| Databáze: | OpenAIRE |
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