Putative mechanisms of kiwifruit on maintenance of normal gastrointestinal function
Autor: | Richard B. Gearry, Lynley Drummond, Simone Bayer |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
medicine.medical_specialty Constipation Gastrointestinal transit time Actinidia Motility Biology Bioinformatics Gastroenterology Industrial and Manufacturing Engineering Irritable Bowel Syndrome 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Irritable bowel syndrome Gastrointestinal tract General Medicine medicine.disease Gastrointestinal Tract 030104 developmental biology Fruit Digestion 030211 gastroenterology & hepatology medicine.symptom Gastrointestinal Motility Gastrointestinal function Food Science |
Zdroj: | Critical Reviews in Food Science and Nutrition. 58:2432-2452 |
ISSN: | 1549-7852 1040-8398 |
DOI: | 10.1080/10408398.2017.1327841 |
Popis: | Kiwifruits are recognized as providing relief from constipation and symptoms of constipation-predominant irritable bowel syndrome (IBS-C). However, the underlying mechanisms, specifically in regards to gastrointestinal transit time and motility, are still not completely understood. This review provides an overview on the physiological and pathophysiological processes underlying constipation and IBS-C, the composition of kiwifruit, and recent advances in the research of kiwifruit and abdominal comfort. In addition, gaps in the research are highlighted and scientific studies of other foods with known effects on the gastrointestinal tract are consulted to find likely mechanisms of action. While the effects of kiwifruit fiber are well documented, observed increases in gastrointestinal motility caused by kiwifruit are not fully characterized. There are a number of identified mechanisms that may be activated by kiwifruit compounds, such as the induction of motility via protease-activated signaling, modulation of microflora, changes in colonic methane status, bile flux, or mediation of inflammatory processes. |
Databáze: | OpenAIRE |
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